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• BIODEGRADABLE POLYMER SYSTEMS FOR SURGERY AND PHARMACY. Design and de- 

velopment of resorbable polymer systems as porous scaffolds of great interest 

in processes of tissue regeneration (Tissue Engineering). The polymer systems 
offers wide spectra of formulations with hydrophobic or hydrophilic character, 

which allows the preparation of 3D scaffolds to be applied in regeneration of 
bone tissue, epidermal or connective tissues, with specific properties. Several 

patents have been registered and are on transfer processes to several compa- 

nies of the biomedical device sector.

• APPLICATION OF SUPERCRITICAL TECHNOLOGIES FOR THE PREPARATION OF POROUS 
. Based on the application of carbonic anhydride in supercritical condi- 
SYSTEMS
tions for the preparation of clean bioactive polymer systems and composites for 

different applications. The technology allows the development of systems for 
Tissue Engineering and drug delivery systems . Also the preparation of systems 

with bioactive compounds sensitive to the pH or temperature are considered in 
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• F-m m B, s r J, r-l lm. Influence of surface 
Most relevant ernndezontesorAledAAnománodríGuezorenzo
features of hydroxyapatite on the adsorption of proteins relevant to bone regeneration 
scientific 
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A. 2013;101:2332-2339.
articles
• mAGAlhes J, sousA rA, mAno JF, reis rl, BlAnCo FJ, sAn román J. Synthesis and charac- í
terization of sensitive hydrogels based on semi-interpenetrated networks of poly[2- 

ethyl-(2-pyrrolidone) methacrylate] and hyaluronic acid.J Biomed Mater Res A. 2013 
Jan;101(1):157-66.

• P h, r-o F, A mr, r G, A C, G-F l 
eniCheeyesrteGAGuilArodríGuezBrAdeloArCíAernándezet 
Al.. Thermosensitive macroporous cryogels functionalized with bioactive chitosan/ 
bemiparin nanoparticles.Macromol Biosci. 2013 Nov;13(11):1556-67.

• r-o F, r G, A mr, l m, W J, s mh, s r J. 
eyesrteGAodrGuezGuilArordhiteloCKtenzelAnomán
Encapsulation of Low Molecular Weight Heparin (bemiparin) into Polymeric nanopar- 
ticles obtained from cationic block copolymers: Properties and cell activity.Journal of 

Materials Chemistry B. 2013;1:850-860.

• reyes-orteGA F, PArrA-ruiz FJ, AveriCK se, rodríGuez G, AGuilAr mr, mAtyJAszeWsKi K, sAn 

romn J. Smart heparin-based bioconjugates synthesized by a combination of ATRP 
and click chemistryPolymer Chemistry. 2013;:2800-2814.




• Preparation and application of bioactive nanoparticles for cáncer therapy. 
Highlights
• Design and preparation of abdominal meses with targeting antibiotic action. 

• Preparation of bilayer dressings for activation of healing processes. 

• New coating coronary stents with high stability and restenosis control.
13
20
• Organization of the XXV congference on Biomaterials for the European society for T 
OR
Biomaterials 8-12 September, with the participation of 956 registered felegates of P
57 countries.
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