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- Magnetic nanoparticles as thermoseeds for the treatment of tumors by hyper-

thermia.

- Magnetic nanoparticles-dendrimer systems for gene transfection.

- Controlled drug release systems in target tissues and organs.

- Nanoparticles for cancer treatment.

Most relevant • m. ColillA, B. González, m. Vallet-Regí. Mesoporous silica nanoparticles for the design
of smart delivery nanodevices. biomaterials Science. 2013;:114-134.
scientific
• D. Arcos, M. Vallet-Regí. Bioceramics for drug deliveryacta mater. 2013;61(3): 890-911.
articles
• s. s-s, m. C, i. i m. v-r. Design and preparation of
ánChezAlCedoolillAzquierdoAnd AlleteGíá
biocompatible zwitterionic hydroxyapatite. J MATER CHEM. 2013;1(11):1595-1606.

• r. mAtheW, C. turdeAn-ionesCu, i. izquierdo-BArBA, A. GArCíA, d. ArCos, m. vAllet-reGí
m. e.. Direct probing of the spatial distribution of phosphate ions in bioactive
And déná
silicate glasses by solid-state NMR. Chemistry of materials . 2013;25(9):1877-1885.

• Gonzlez B, ColillA m, vAllet-reGí m. Design of in vitro bioactive hybrid materials from
í
the first generation of amine dendrimers as nanobuilding blocks.Chemistry. 2013 Apr
8;19(15):4883-95.

Highlights
The most important achievements during 2013 include the preparation, optimiza-
tion and implantation of three-dimensional scaffolds based on various bioceramics,
í
as well as of new biologically functionalized mesoporous systems with osteogenic
agents. The launch of a new research area in nanotechnology, for the development

of non-viral magnetic vectors for gene transfection and antitumoral therapy, is also

highlighted.
During 2013 GIBI group has developed different research lines in the frame of

different national and international research projects including MAT2012-35556,
S2009/MAT-1472, FP7-PEOPLE-2007-2-2-ERG, CSO2010-11384-E, AP/042845/11

and MAT2008-00736. GIBI group is member of the Research Institute of “Hospi-
tal 12 de Octubre (i+12)”, Research Network of Excellence of Madrid Community í

(Spain) and the Spanish and European Network of Excellence for prevention and

treatment of osteoporotic fractures (Agening). Moreover, GIBI group has been also
involved in science spreading actions during 2013, specifically in organizing an In-

ternational symposium on Agening and Osteosporosis (Fundación Ramón Areces).
During 2013, GIBI group has published 18 original research articles, 4 reviews,

and 1 book chapters and 2 complete books enclosed in smart biomaterials for drug íí
delivery and bone tissue regeneration purposes:

• “Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials

and Bone Tissue Engineering” by Mara Vallet-Reg; Miguel Manzano García;
Montserrat Colilla CRC Press, 2013. ISBN 9781439883075.
13
20
T
• “Biomaterials”, from the series “What do we know about...?” from the Spanish OR
National Research Council (CSIC) by Maria Vallet-Reg ISBN 978-84-00-09756-1.
P
RE
Furthermore, recently the book “Bio-Ceramics with Clinical Applications” has just L
A
been published by John Wiley & Sons Ltd, Chichester, UK, edited by Prof. Maria NU
Vallet-Regi (ISBN: 978-111840675). This book provides a cohesive, structured ac- N
A
count of the advances and new applications of bioceramics in the clinical world. N /
B
Finally, Mara Vallet-Reg (IP) has been awarded with the IUPAC 2013 Prize as Dis- -B
tinguished Woman in Chemistry or Chemical Engineering and the Prize Miguel Cata- R
BE
ln 2013.
CI

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